Peripheral T-cell Lymphoma-Unspecified (PTCL-U) Presenting with Hypereosinophilic Syndrome and Pleural Effusions.
10.3904/kjim.2006.21.1.57
- Author:
Won CHOI
1
;
Yeon Hee PARK
;
Kwang Hyun PAIK
;
Yoon Hwan CHANG
;
Seung Sook LEE
;
Baek Yeol RYOO
;
Sung Hyun YANG
Author Information
1. Department of Internal Medicine, Korea Institute of Radiological and Medical Sciences, Seoul, Korea. yhpark@kcch.re.kr
- Publication Type:Case Report
- Keywords:
Hypereosinophilic syndrome;
Lymphoma;
T-Cell;
Peripheral;
Paraneoplastic syndrome
- MeSH:
Recurrence;
Pleural Effusion/*etiology;
Lymphoma, T-Cell, Peripheral/complications/*diagnosis;
Liver Neoplasms/complications/*diagnosis;
Hypereosinophilic Syndrome/*etiology;
Humans;
Female;
Fatal Outcome;
Adult
- From:The Korean Journal of Internal Medicine
2006;21(1):57-61
- CountryRepublic of Korea
- Language:English
-
Abstract:
Hypereosinophilic syndrome (HES) is a clinical disorder characterized by persistent eosinophilia and systemic involvement, in which a specific causative factor for the eosinophilia cannot be verified during a certain period of time. There have been only a few reported cases of this syndrome associated with malignant lymphoma. We report a case of peripheral T-cell lymphoma-unspecified with hypereosinophilic syndrome. The patient was a 42-year-old woman with an uncontrolled fever and a sore throat. Eosinophilia was observed on the peripheral blood smear. We confirmed the diagnosis by bone marrow and liver biopsies: A bone marrow aspiration demonstrated markedly increased eosinophils (24.8%), and a liver biopsy demonstrated infiltration by scattered eosinophils and atypical lymphoid cells, which were confirmed to be T-cell lymphoma cells. This case was a distinctive presentation of peripheral T-cell lymphoma with hypereosinophilic syndrome, probably due to a paraneoplastic condition.
