Detection and analysis of HAV-HEV, HGV infection in patients with viral hepatitis.
- Author:
Liang-Shi XIONG
1
;
Su-Fen CUI
;
Jing-Guo ZHOU
;
Yan XING
Author Information
- Publication Type:Journal Article
- MeSH: Antibodies, Viral; blood; China; epidemiology; Female; GB virus C; isolation & purification; Hepatitis A; epidemiology; virology; Hepatitis A virus; isolation & purification; Hepatitis E; epidemiology; virology; Hepatitis E virus; isolation & purification; Hepatitis Viruses; isolation & purification; Hepatitis, Viral, Human; epidemiology; virology; Humans; Male; Superinfection
- From: Chinese Journal of Hepatology 2004;12(7):395-396
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVETo study the simple infection and super/co-infection of HAV-HEV, HGV in patients with viral hepatitis.
METHODSUsing EIA method to detect anti-HAV IgM, HBV serum markers, anti-HCV IgM, anti-HDV IgM, anti-HEV IgM, anti-HGV IgM in viral hepatitis patients with different clinical types.
RESULTSSeventy-three percent patients (154/210) had HBV infection markers, twenty-nine percent patients (61/210) had HAV infection marker, eight percent patients (17/210) had HCV, HDV infection markers, ten percent patients (21/210) had HEV infection and seven percent patients (15/210) had HGV infection. Only nine percent patients (20/210) had viral hepatitis serum markers negative. In all clinical types, sixty-one percent patients had only one type hepatitis virus infection, thirty-two percent patients had two types of hepatitis virus super/co-infection, six percent patients had three types of hepatitis virus super/co-infection. Super/co-infection often occurred in patients who had cirrhosis or hepatic failure.
CONCLUSIONHBV and HAV infection is very common in viral hepatitis patients, whereas HCV, HDV, HEV and HGV infection is relatively low; double super/co-infection of HAV-HEV, HGV frequently occurs in severe patients with viral hepatitis.
