Evaluation of specific toxicity of pertussis component of DPT vaccine by mouse weight gain test, leukocytosis promoting factor test and limulus amebocyte lysate, assay
- Author:
Phuong Lan Nguyen
- Publication Type:Journal Article
- Keywords:
vaccine
- MeSH:
Diphtheria-Tetanus-Pertussis Vaccine;
Whooping Cough;
toxicity
- From:Journal of Preventive Medicine
2002;12(5):11-16
- CountryViet Nam
- Language:Vietnamese
-
Abstract:
17 final bulks of pertussis suspension, combined with AlPO4 were evaluated for specific toxicity by MWG test, LPF test and MICRO LAL test. Results showed that: there was relationship between potency and specific toxicity of the vaccine. LPF test was found more reliable than MICRO LAL test when compared to MWG test.
