The application of recombinant Bacillus Calmette-Guérin vaccine and its vector in infectious disease.
- Author:
Tursun ZULPIYA
1
;
Jianbing DING
1
Author Information
1. The College of Pre-clinic, Xinjiang Medical University, Urumqi 830011, China.
- Publication Type:Journal Article
- MeSH:
AIDS Vaccines;
genetics;
immunology;
Antigens, Bacterial;
genetics;
immunology;
BCG Vaccine;
genetics;
immunology;
metabolism;
Communicable Disease Control;
methods;
Genetic Vectors;
genetics;
HIV Infections;
prevention & control;
HIV-1;
Mycobacterium tuberculosis;
Recombinant Proteins;
biosynthesis;
genetics;
immunology;
Tuberculosis;
prevention & control;
Vaccines, Synthetic;
immunology
- From:
Journal of Biomedical Engineering
2013;30(5):1136-1140
- CountryChina
- Language:Chinese
-
Abstract:
Recent studies show that the vector of recombinant Bacillus Calmette-Guérin (rBCG) has a series of advantages. With exogenous gene and vaccine in one inoculation, it can obtain strong and persistent immune response at one time so that BCG is considered as a kind of ideal vector for live recombinant vaccine. This review outlines the application of rBCG vaccine and its vector in infectious diseases caused by bacteria, viruses, other microorganisms and parasites.
