Experimental research and analysis on dielectric properties of blood in anemia mice.
- Author:
Ben SHEN
;
Quiyan LIANG
;
Weiqi GAO
;
Chu YOU
;
Mengqi HONG
;
Qing MA
- Publication Type:Journal Article
- MeSH:
Anemia;
blood;
Animals;
Blood Physiological Phenomena;
Electric Conductivity;
Electric Impedance;
Hematocrit;
Mice
- From:
Journal of Biomedical Engineering
2013;30(6):1186-1190
- CountryChina
- Language:Chinese
-
Abstract:
The conductivity and permittivity of blood in mice were measured by the AC electrical impedance method at frequency range of 0.1-100MHz, and then the changes of the Cole-Cole parameters of dielectric spectra of blood from phenylhydrazine-induced anemia mice were observed by numerical calculation and curve fitting residual analysis of the Cole-Cole equation. The results showed that hematocrit (Hct) of the mice with phenylhydrazine injection was significantly reduced; the permittivity(epsilon) spectroscopy of blood moved to the low insulating region and its permittivity decreased; conductivity (kappa) spectrum curve of blood moved to the high conductivity zone and conductivity increased; the 2nd characteristic frequency was lower than that in the normal group. There was phenylhydrazine dose dependent in the changes of the Cole-Cole parameters of dielectric spectra of blood.
