Evolution of Health-Related Quality of Life in Breast Cancer Patients during the First Year of Follow-Up.
10.4048/jbc.2013.16.1.104
- Author:
David MORO-VALDEZATE
1
;
Salvador PEIRO
;
Elvira BUCH-VILLA
;
Antonio CABALLERO-GARATE
;
M Dolores MORALES-MONSALVE
;
Angel MARTINEZ-AGULLO
;
Felix CHECA-AYET
;
Joaquin ORTEGA-SERRANO
Author Information
1. Department of Surgery, Hospital Cinico Universitario de Valencia, Valencia, Spain. davidmoro78@gmail.com
- Publication Type:Multicenter Study ; Original Article
- Keywords:
Breast neoplasms;
Quality of life;
Questionnaires
- MeSH:
Breast;
Breast Neoplasms;
Cohort Studies;
Female;
Follow-Up Studies;
Humans;
Prospective Studies;
Quality of Life;
Weights and Measures;
Surveys and Questionnaires
- From:Journal of Breast Cancer
2013;16(1):104-111
- CountryRepublic of Korea
- Language:English
-
Abstract:
PURPOSE: The objective of this study was to describe the evolution of health-related quality of life (HRQOL) in a cohort of breast cancer patients over 1 year after surgery and to analyse the predictive ability of HRQOL measurement instruments. METHODS: Observational, multicenter and prospective study of a cohort of breast cancer patients, assessing HRQOL at 1, 6, and 12 months after surgery using three questionnaires: EuroQol-5D-3L, EORTC QLQ-C30, and EORTC QLQ-BR23. RESULTS: A total of 364 women participated in the study. Visual Analogue Scale (VAS) scores from the EuroQol improved (1 month vs. 1 year: 70 vs. 80; p<0.0001); however, the EuroQol score showed no significant change (0.81 vs. 0.83; p=0.1323). In contrast, Global Health Status on the EORTC QLQ-C30 improved (66.67 vs. 100.00; p<0.0001), as did all of this instrument's scales and most of its independent items. The EORTC QLQ-BR23 dimensions showed improvement, except for sexual functioning (100.00 vs. 86.67; p=0.0030) and future perspective (33.33 vs. 66.67; p<0.0001). Patients with good HRQOL outcomes at 1 month showed improved levels of HRQOL at 1 year; HRQOL measured at 1 month was predictive of HRQOL at 1 year. CONCLUSION: HRQOL improved during the follow-up period. Likewise, HRQOL measurement instruments can predict early HRQOL.
