Two novel isocoumarins from Erigeron breviscapus.
- Author:
Jing LI
1
;
De-Quan YU
Author Information
1. Key Laboratory of the Ministry of Education for Bioactive Substances and Resources Utilization of Chinese Herbal Medicine, Institute of Materia Medica, Peking Union Medical College & Chinese Academy of Medical Sciences, Beijing 100050, China.
- Publication Type:Journal Article
- MeSH:
Erigeron;
chemistry;
Isocoumarins;
chemistry;
isolation & purification;
Molecular Structure;
Plants, Medicinal;
chemistry
- From:
Acta Pharmaceutica Sinica
2013;48(7):1128-1130
- CountryChina
- Language:Chinese
-
Abstract:
Two novel isocoumarins, erigeronone C (1) and D (2), were isolated from the ethanol extract of the whole plant of Erigeron breviscapus (Vant.) Hand.-Mazz (Compositae). Their structures were respectively elucidated as 8, 9-dihydroxypyrano [3, 2-c] isochromen-4, 6-dione (1) and 4, 7-dihydroxy-3-(3-hydroxy-4-oxo-4H-pyran-2-yl)-1H-isochromen-1-one (2) on the basis of spectral analyses. Both structures of 1 and 2 possess a gamma-pyrone moiety and that is rare in natural products.