The results of combined therapeutic modalities for hepatoblastoma.
- Author:
Airi HAN
1
;
Jung Tak OH
;
Seok Joo HAN
;
Seung Hoon CHOI
;
Eui Ho HWANG
Author Information
1. Department of Pediatric Surgery, Yonsei University College of Medicine, Seoul, Korea. ehhwang@yumc.yonsei.ac.kr
- Publication Type:Original Article
- Keywords:
Hepatoblastoma;
Surgical resection;
Preoperative chemotherapy
- MeSH:
Chemotherapy, Adjuvant;
Diagnosis;
Drug Therapy;
Hepatoblastoma*;
Humans;
Mortality;
Prognosis
- From:Journal of the Korean Association of Pediatric Surgeons
2001;7(1):37-41
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
In hepatoblastoma, encouraging cure rates have been achieved with recent advances in chemotherapy and surgical techniques. The aim of this study is to evaluate the role of combined therapeutic modalities and surgical resection in hepatoblastoma. Fifteen cases of hepatoblastoma were treated from January 1993 to August 2000. Six patients had resectable tumors at initial diagnosis. All underwent surgical resection and in four patients postoperative adjuvant chemotherapy was needed. Nine out of 15 patients had unresectbale tumors at initial diagnosis, and preoperative chemotherapy was applied. There was one operative mortality and 14 patients showed good prognosis after surgery. Although various treatment modalities should be combined for the unresectable hepatoblastoma, surgical resection remains the major curative procedure.
