Hyaluronic acid-based carriers for tumor targeted delivery system.
- Author:
Li-peng QIU
1
;
Miao-miao LONG
1
;
Da-wei CHEN
1
Author Information
1. School of Pharmacy, Shenyang Pharmaceutical University, Shenyang 110016, China.
- Publication Type:Journal Article
- MeSH:
Animals;
Antineoplastic Agents;
administration & dosage;
chemistry;
therapeutic use;
Drug Carriers;
Drug Delivery Systems;
Humans;
Hyaluronic Acid;
chemistry;
Molecular Structure;
Nanoparticles;
Neoplasms;
drug therapy
- From:
Acta Pharmaceutica Sinica
2013;48(9):1376-1382
- CountryChina
- Language:Chinese
-
Abstract:
Hyaluronic acid (HA) as anticancer drug carrier has become the new hot point in the field of tumor-targeted drugs delivery system in recent years. Tumor therapeutic agents could be transmitted into cells because of hyaluronic acid innate ability to recognize specific cellular receptors that overexpressed on tumor cells surface. This review introduces the basic properties and physiology foundation of hyaluronic acid. Recent research developments based on different forms of HA tumor-targeted drugs delivery systems are reviewed in particular.
