Association of hepatitis B virus infection and cirrhosis with liver metastasis in colorectal cancer.
- Author:
Hong-gang QIAN
1
;
Ji ZHANG
;
Jia-hua LENG
;
Guo-quan ZHOU
;
Jian-hui WU
;
Xiu-yun TIAN
;
Yong YANG
;
Chun-yi HAO
Author Information
- Publication Type:Journal Article
- MeSH: Adult; Aged; Aged, 80 and over; Colorectal Neoplasms; pathology; virology; Female; Hepatitis B; complications; Hepatitis B virus; Humans; Liver Cirrhosis; complications; Liver Neoplasms; secondary; virology; Male; Middle Aged; Neoplasm Metastasis; Retrospective Studies; Survival Rate; Young Adult
- From: Chinese Journal of Gastrointestinal Surgery 2010;13(3):202-204
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVETo explore the relationship of hepatitis B virus (HBV) infection and cirrhosis with liver metastasis in colorectal cancer.
METHODSClinical date of 1176 colorectal cancer patients undergone surgical treatment in the Peking University School of Oncology between January 1999 and August 2004 were analyzed retrospectively to investigate the impact of HBV infection and cirrhosis on the occurrence of liver metastasis and prognosis of patients.
RESULTSThe incidence of liver metastasis was 8.8% (10/114) in the HBV infection group and 23.9% (254/1062) in the non-infection group (P<0.01). The 5-year survival rates of these two groups were 54.2% and 60.7% ( P>0.05). The incidence of liver metastasis was 3.8% (1/26) in the cirrhotic group and 22.9% (263/1150) in the non-cirrhotic group (P<0.05). The 5-year survival rates of these two groups were 60.9% and 59.9% ( P>0.05).
CONCLUSIONBoth hepatitis B virus infection and cirrhosis are associated with less liver metastasis in colorectal cancer, but have no impact on the survival.
