Recent advances in treatment of glial scar-induced inhibition of nerve regeneration.
- Author:
Jian-Xiang ZHANG
1
;
Wei-Wei HU
;
Zhong LIU
Author Information
1. College of Medicine, Zhejiang University, Hangzhou 310058,China.
- Publication Type:Journal Article
- MeSH:
Animals;
Astrocytes;
pathology;
Brain Injuries;
pathology;
physiopathology;
Cicatrix;
prevention & control;
Humans;
Nerve Regeneration;
Neuroglia;
pathology;
Neuronal Plasticity;
physiology;
Neurons;
physiology;
Proteoglycans;
metabolism;
Spinal Cord Injuries;
pathology;
physiopathology
- From:
Journal of Zhejiang University. Medical sciences
2009;38(6):639-643
- CountryChina
- Language:Chinese
-
Abstract:
Glial scar formed by central nervous system (CNS) injury is the main inhibitory barrier of nerve regeneration. How to promote axonal regeneration after injury,how to accelerate neural network reconstruction and how to improve brain function recovery have become a hot problem to be solved in the field of neuroscience. This article focuses on the recent advances of therapeutic strategies for axonal regeneration.