VEGF and central nervous system diseases.
- Author:
Lu-Yi ZHANG
1
;
Yan-Ying FAN
;
Zhong LIU
Author Information
1. Department of Pharmacology, College of Medicine, Zhejiang University, Hangzhou 310058, China.
- Publication Type:Journal Article
- MeSH:
Alzheimer Disease;
metabolism;
Animals;
Brain Ischemia;
metabolism;
Humans;
Neuroprotective Agents;
pharmacology;
Parkinson Disease;
metabolism;
Vascular Endothelial Growth Factor A;
classification;
metabolism;
physiology
- From:
Journal of Zhejiang University. Medical sciences
2009;38(6):644-648
- CountryChina
- Language:Chinese
-
Abstract:
Vascular endothelial growth factor (VEGF or VEGF-A) is a hypoxia induced angiogenic growth factor that is potent in neurotrophy,neuroprotection, anti-apoptosis and cell proliferation. Recent reports suggest that VEGF is related to many central nervous system diseases, such as cerebral ischemic disease, Alzheimer's disease and Parkinson's disease. Further study of the relationship between VEGF and central nervous system diseases,and investigation of VEGF related drugs will shed light on a new way for treatment of central nervous system diseases.
