Ion channelopathies and inherited arrhythmia.
- Author:
Ming-jun FENG
1
;
Hui-min CHU
Author Information
1. Ninbo First Hospital, Affiliated Medical of Ninbo University, Ninbo, China.
- Publication Type:Journal Article
- MeSH:
Animals;
Arrhythmias, Cardiac;
genetics;
physiopathology;
Channelopathies;
genetics;
physiopathology;
Humans;
Ion Channels;
genetics;
physiology;
Mutation
- From:
Journal of Zhejiang University. Medical sciences
2010;39(1):97-102
- CountryChina
- Language:Chinese
-
Abstract:
Ion channelopathies are the mainly etiopathogenisis of inherited arrhythmia. Those arrhythmia syndromes are commonly caused by ion channel gene mutation, which can be classified as sodium,potassium and calcium ion channel mutation.Changes in the genes encoding for cardiac ion channel subunits produce modification in the function of the channels, and cause the dysfunctions of cardiac electrical activity; and the clinical manifestation is malignant arrhythmia.
