MRI scan of striatum volume in healthy adults.
- Author:
Jing-feng XU
1
;
Xiao-jun XU
;
Qi-dong WANG
;
Yi-lei ZHAO
;
De-xing KONG
;
Min-ming ZHANG
Author Information
- Publication Type:Journal Article
- MeSH: Adolescent; Adult; Age Factors; Aged; China; Corpus Striatum; anatomy & histology; Female; Humans; Magnetic Resonance Imaging; Male; Middle Aged; Reference Values; Sex Factors; Young Adult
- From: Journal of Zhejiang University. Medical sciences 2010;39(2):130-135
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVETo examine the age, sex, and hemispheric differences in volume of the striatum by MRI in healthy adults.
METHODSThe volumes of the bilateral caudate nucleus and putamen were measured on MR images in 100 healthy right-handed adults (18-70 y).
RESULTSThe volume of bilateral caudate nucleus and putamen in healthy adults was (8.42 +/-0.88) cm(3) and (8.90 +/-0.89) cm(3), which were decreased with aging (for caudate nucleus r=-0.727, P<0.001; for putamen r=-0.709, P<0.001). The average annual shrinkage rate was 0.52 % in the caudate nucleus and 0.50 % in the putamen. There were no gender differences in the volume of the striatum, however, the age-related shrinkage of the striatum was more evident in men than that in women. The volume of the left caudate nucleus (t=4.43, P<0.001) and the putamen (t=4.88, P<0.001) was greater than that of its right counterpart.
CONCLUSIONBilateral age-related shrinkage of the striatum is found in healthy adults, which is more evident in men than that in women. In both sexes, significant leftward asymmetry in volume of the caudate nucleus and the putamen is found.
