Risperidone-induced Gingival Bleeding in a Pediatric Case: A Dose-dependent Side Effect.
10.9758/cpn.2016.14.2.210
- Author:
Sabri HERGÜNER
1
;
Hatice Yardım ÖZAYHAN
;
Emire Aybuke ERDUR
Author Information
1. Department of Child and Adolescent Psychiatry, Meram Faculty of Medicine, Necmettin Erbakan University, Konya, Turkey. herguners@yahoo.com
- Publication Type:Case Report
- Keywords:
Bleeding;
Risperidone;
Child;
Adverse effects
- MeSH:
Child;
Hemorrhage*;
Humans;
Risperidone;
Serotonin
- From:Clinical Psychopharmacology and Neuroscience
2016;14(2):210-211
- CountryRepublic of Korea
- Language:English
-
Abstract:
There are several case reports on risperidone-related bleeding; however, to our knowledge, there is no report about gingival bleeding associated with risperidone in the literature. We presented a case who experienced gingival bleeding when risperidone dose was increased to 0.5 mg/day, and subsided after decreasing the dose to 0.25 mg/day, suggesting a dose-dependent side-effect. The bleeding side effect of risperidone might be caused by several mechanisms, including 5-hydroxytryptamine 2A receptor antagonism. Although bleeding associated with risperidone is rarely reported, clinicians should be aware of this side effect.