Clinical characteristics of patients with juvenile localized scleroderma.
- Author:
Qiu-Ning SUN
1
;
Wei DU
;
Bin HU
;
Pai LIU
;
Xie YUAN
Author Information
- Publication Type:Journal Article
- MeSH: Adolescent; Antibodies, Antinuclear; blood; Autoimmune Diseases; complications; Child; Child, Preschool; Female; Humans; Infant; Male; Retrospective Studies; Scleroderma, Localized; diagnosis; immunology; pathology
- From: Acta Academiae Medicinae Sinicae 2009;31(1):48-50
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVETo investigate the clinical characteristics of juvenile localized scleroderma (JLS).
METHODSThe clinical data of 100 outpatients with JLS who were admitted to PUMC Hospital from 2000 to 2008 were retrospectively analyzed.
RESULTSOf a total of 100 cases, 51 (51%) were confirmed as linear scleroderma, 26 (26%) as plaque morphea, 26 (26%) as deep morphea, 12 (12%) as generalized morphea, and 15 (15%) as a mixed subtype. Nine patients (9%) had family histories of rheumatic or autoimmune diseases, while 16 (16%) might be triggered by unknown factors. Totally 84 patients underwent antinuclear antibody tests and 38 patients (45.2%) had positive results.
CONCLUSIONSLinear scleroderma are the most frequent subtype of JLS. Localized scleroderma may be associated with some autoimmune-related causes.
