BK virus and renal transplantation.
- Author:
Hang LIU
1
;
Yi SHI
;
Chao-yang LI
;
Jian-li WANG
Author Information
1. Department of Transplantation, Tianjin First Center Hospital, Tianjin 300192, China. liuhang66@yahoo.com.cn
- Publication Type:Journal Article
- MeSH:
BK Virus;
physiology;
Humans;
Kidney;
pathology;
virology;
Kidney Transplantation;
Polyomavirus Infections;
diagnosis;
pathology;
therapy;
Postoperative Complications;
diagnosis;
pathology;
therapy;
virology;
Risk Factors;
Tumor Virus Infections;
diagnosis;
pathology;
therapy;
Virus Activation
- From:
Acta Academiae Medicinae Sinicae
2009;31(3):269-275
- CountryChina
- Language:Chinese
-
Abstract:
BK virus (BKV) is a subtype of papovaviridae. The latent and asymptomatic infection of BKV is common among healthy people. The incidence of BKV re-activation in renal transplant recipients ranges 10%-68%. About 1%-7% of renal transplant recipients will suffer from BKV-associated nephropathy (BKVAN), and half of them will experience graft failure. This paper summarizes the re-activation mechanism of BKV as well as the risk factors, pathology, diagnosis, and treatment of BKVAN.
