Effect of electroacupuncture on expression of IFN-gamma-like immunoreactive substance in spinal cord of the rat .
- Author:
Ge HU
1
;
Zuo-Jun YANG
;
Hui-Qin DUAN
;
Li-Yun GAO
;
Xiang MU
;
Yu-Liang LI
Author Information
- Publication Type:Journal Article
- MeSH: Acupuncture Points; Animals; Electroacupuncture; Interferon-gamma; Rats; Spinal Cord
- From: Chinese Acupuncture & Moxibustion 2005;25(7):513-516
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVETo observe effect of electroacupuncture at "Zusanli" (ST 36) on expression of interferon-gamma (IFN-gamma)-like immunoreactive substance in spinal cord of the rat and to probe the mechanism.
METHODSThe IFN-gamma-like immunoreactive positive cell number in spinal cord of the rat was investigated with immunohistochemical SP method and microscopy.
RESULTSAfter electroacupuncture at "Zusanli" (ST 36), IFN-gamma-like immunoreactive positive cell number in the spinal cord of the rat with electroacupuncture plus immunosuppression did not significantly change (P > 0.05). The number of positive cells in the dorsal horn in the rats with immunosuppression was significantly less than that in the normal control group (P < 0.05) with no significant change in other parts and with no significant difference between the electroacupuncture group and the control group (P > 0.05).
CONCLUSIONElectroacupuncture at "Zusanli" (ST 36) can increase expression of IFN-gamma-like immunoreactive substance in spinal cord of the rat, and acupuncture activates the nerve-immunoregulative network possibly by IFN-gamma as medium.
