OBJECTIVETo probe into essence of meridians.

METHODSTo examine meridians, acupoints, brain and relative organs by SQUID and fMRI, and to analyze the results.

CONCLUSIONA relative stable circular current of electromagnetic and chemical oscillation along the low electric resistance pathway was found. Competition of different frequency oscillation often yield resonance in some positions of the human body so as to form "oscillatory network" and "strange point" with the electromagnetic and chemical oscillation circulating dominant position in the body, which is possibly meridians and acupoints with regulative actions. The brain is the center of meridians. In different physiological or pathological process, characteristic changes and negatively correlative phenomenon of electromagnetic spectrum at acupoints and the brain are possibly key mechanisms in dynamic regulation of meridians.