Serological Study of An Imported Case of Middle East Respiratory Syndrome and His Close Contacts in China, 2015.

Author: Wen Ling WANG ^{1
,

2} ; Hui Juan WANG ¹ ; Yao DENG ¹ ; Tie SONG ³ ; Jia Ming LAN ¹ ; Gui Zhen WU ¹ ; Chang Wen KE ³ ; Wen Jie TAN ¹ ;
Author Information

1. Key Laboratory of Medical Virology and Virus Disease, National Health and Family Planning Commission of the People's Republic of China
2. National Institute for Viral Disease Control and Prevention, Chinese Center for Disease Control and Prevention, Beijing 102206, China.
3. Guangdong Provincial Center for Disease Control and Prevention, Guangzhou 511430, Guangdong, China.
Publication Type:Case Reports
MeSH: Antibodies, Neutralizing; blood; Antibodies, Viral; blood; China; epidemiology; Contact Tracing; Coronavirus Infections; blood; epidemiology; transmission; Enzyme-Linked Immunosorbent Assay; Humans; Immunoglobulin G; blood; Immunoglobulin M; blood; Male; Republic of Korea; epidemiology; Travel
From: Biomedical and Environmental Sciences 2016;29(3):219-223
CountryChina
Language:English
Abstract: The first imported Middle East respiratory syndrome (MERS) case in China was identified in May 2015. We determined the kinetics of antibody (IgG and IgM) and neutralizing antibodies against MERS-coronavirus (MERS-CoV) in this case before discharge. Moreover, no seroconversion was found among 53 close contacts by anti-MERS IgG antibody enzyme-linked immunosorbent assay (ELISA) of paired serum samples. These findings suggest that neither community nor nosocomial transmission of MERS-CoV occurred in China.