Imaging the neuromuscular junction over the past centuries.
- Author:
Ju LU
1
;
Jeff W LICHTMAN
Author Information
1. Department of Molecular and Cellular Biology, Harvard University, Cambridge, MA 02138, USA.
- Publication Type:Journal Article
- MeSH:
Diagnostic Imaging;
Humans;
Neuromuscular Junction;
anatomy & histology;
physiology;
Receptors, Nicotinic;
physiology;
Synaptic Vesicles;
physiology
- From:
Acta Physiologica Sinica
2007;59(6):683-696
- CountryChina
- Language:English
-
Abstract:
The neuromuscular junction (NMJ) has been studied for over a century as a model system for synaptic anatomy, physiology and development. Much of our knowledge of the NMJ has been obtained through imaging techniques, some of which were developed particularly to visualize this synapse's structure and function. In this paper we review the historical development of research on some key aspects of the NMJ, including its structure, nicotinic acetylcholine receptor distribution, the process of synaptic vesicle release, and its development.
