Research progress of ellagitannin intestinal metabolite urolithins.

Author: Ben-Hong ZHOU ¹ ; Zhen-Peng QIU ² ; Hui-Lan YI ¹ ; Ding-Shan ZHOU ¹ ; Jing WANG ¹ ; Yue WU ¹
Author Information

1. Renmin Hospital of Wuhan University, Wuhan 430060, China.
2. Key Laboratory of Traditional Chinese Medicine Resources and Traditional Chinese Medicine Compounds, Ministry of Education, Hubei University of Chinese Medicine, Wuhan 430065, China.
Publication Type:Journal Article
Keywords: biological activity; distribution; metabolite; urolithins
From: China Journal of Chinese Materia Medica 2016;41(16):2968-2974
CountryChina
Language:Chinese
Abstract: Ellagitannins is a kind of phenolic compounds with many biological activities. Recent studies have found that the effective ingredients of these compounds have close relationship with their colon-derived bacteria metabolites, that is urolithins. The objective of this study was to review the structure characteristics, types and distribution of urolithins, improvement in diseases related to prostate, breast and colon, as well as anti-cancer, anti-oxidation, anti-inflammation and other biological activities. The present review will lay the foundation for development and utilization of urolithins.