Sesquiterpenes from stems of Schisandra henryi var. henryi.
- Author:
Jie-Wen ZHOU
1
;
Jin-Long DU
2
;
Xian-Feng HOU
2
;
La-Mei ZHENG
1
;
Dan LIU
1
;
Hui-Li LIU
3
;
Jie WANG
3
;
Jun-Yi HU
2
;
Ying-Qian XU
2
;
Jia-Chun CHEN
1
;
Jin-Bo FANG
1
Author Information
- Publication Type:Journal Article
- Keywords: Schisandra henryi var. henryi; cadinane-type; eudesmane-type; guaiane-type; sesquiterpenes
- From: China Journal of Chinese Materia Medica 2016;41(16):3049-3054
- CountryChina
- Language:Chinese
- Abstract: The dried stems of Schisandra henryi var. henryi were extracted with 95% ethanol and the extracts were further subjected to partition, affording the ethyl acetate extracts(EtOAc Extrs.).The EtOAc Extrs.were separated and purified with silica gel and octadecyl-silylated silica gel column chromatography, preparative HPLC and preparative TLC. Thirteen known compounds were obtained and identified by spectral methods including MS and NMR, all of which were elucidated as t-cadinol(1), cadinane-4β,5α,10β-triol(2), cadinane-5α, 10α-diol-2-ene(3), oxyphyllenodiols A(4), 1β, 4β-dihydroxyeudesman-11-ene(5), cyperusol C(6), (7R)-opposit-4(15)-ene-1β,7-diol(7), dysodensiol E(8), epi-guaidiol A(9), aromadendrane-4β,10β-diol(10), tricyclohumuladiol(11), caryolane-1,9β-diol(12), and guaidiol A(13). Compounds 3, 5-10, and 13 were separated from the genus for the first time, while compounds 1-13 were separated from this species for the first time.
