The efficacy of preoperative portal vein embolization for extended hepatectomy: a meta-analysis.
- Author:
Wen-yi ZHAO
1
;
Meng LUO
;
Yong-wei SUN
;
Qing XU
;
Wei CHEN
;
Gang ZHAO
;
Zhi-yong WU
Author Information
- Publication Type:Journal Article
- MeSH: Embolization, Therapeutic; Hepatectomy; Humans; Liver Failure; etiology; prevention & control; Portal Vein; Postoperative Complications; prevention & control; Preoperative Care; Survival Analysis; Treatment Outcome
- From: Chinese Journal of Surgery 2008;46(19):1460-1464
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVETo investigate the clinical value of preoperative portal vein embolization (PVE) for extended hepatectomy.
METHODSA comprehensive Pubmed, Medline and Ovid database search to identify all registered literature on portal vein embolization. Meta-analysis was performed to assess the result of PVE.
RESULTSA total of 9 literatures provided data sufficiently enough for analysis involving in 494 patients. The results showed that postoperative liver failure was higher in the non-PVE group than the PVE group, but there was no difference in postoperative mortality between the PVE and non-PVE group; in sub-category analysis of hepatocellular carcinoma and liver metastasis of colorectal cancer, there was no difference in postoperative 1, 3 and 5-year survival rate between the PVE group and non-PVE group; 1 literature about liver metastasis of colorectal cancer show there was significant difference in postoperative metastasis between the PVE and non-PVE group; several patients after PVE didn't performed hepatectomy due to disease progress.
CONCLUSIONSPVE is a safe and effective procedure to prevent postresection liver failure due to insufficient liver remnant, but surgeon should be cautious to choose the patient for PVE.
