Study on synthesis of some compounds of azometine base, derivatives of vanilline and exploration of its biological effects
- Author:
Thu Kim Nguyen
- Publication Type:Journal Article
- Keywords:
drug
- MeSH:
Pharmaceutical Preparations;
Relative Biological Effectiveness
- From:Pharmaceutical Journal
1999;274(2):9-10
- CountryViet Nam
- Language:Vietnamese
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Abstract:
Synthesis research and test on biological activities of some azomethines from vanilline and 5-Nitro vanilline. 10 azomethines can be obtained by condensing vanilline and 5-Nitro Vanilline with aromatic amines such as aniline, pAB, p.Bromoe aniline, or.Toluidin, anthraniclic acid. The structures of obtained products have been characterized by element analyses and IR, UV spectroscopy. The compounds have been tested for antibacterial activities on positive gram bacteria rather than on negative ones. Azomethines of 5-Nitro vanillin have great effect in antibacterial and antifungal activities.
