A Case of Spitzoid Melanoma with Lymph Node Metastasis in a Child.
10.3346/jkms.2012.27.4.454
- Author:
Jong Yeob KIM
1
;
Jae Eun CHOI
;
Hyo Hyun AHN
;
Young Chul KYE
;
Soo Hong SEO
Author Information
1. Department of Dermatology, Korea University College of Medicine, Seoul, Korea. dermaseo@yahoo.co.kr
- Publication Type:Case Reports
- Keywords:
Child;
Lymph Node Metastasis;
Spitz Nevus;
Spitzoid Melanoma
- MeSH:
Antineoplastic Agents/therapeutic use;
Child, Preschool;
Female;
Humans;
Interferon-alpha/therapeutic use;
Lymphatic Metastasis;
Melanoma/drug therapy/*pathology/surgery;
*Nevus, Epithelioid and Spindle Cell;
Recombinant Proteins/therapeutic use;
Skin Neoplasms/drug therapy/*pathology/surgery
- From:Journal of Korean Medical Science
2012;27(4):454-457
- CountryRepublic of Korea
- Language:English
-
Abstract:
The distinction of a spitz nevus from a melanoma can be difficult and in some cases, impossible. A misdiagnosed spitz nevus can metastasize and lead to fatal outcomes, especially in children. A 5-yr-old girl presented with a 1-yr history of a solitary pinkish nodule on her left hand. On physical examination, she had a palpable left axillary lymph node. We performed biopsy and checked 3 sentinel lymph nodes (SLN) on her axillary area. The biopsy specimen showed multiple variably sized and shaped nests with large spindle or polygonal cells and SLN biopsy showed 3 of 3 lymph nodes that were metastasized. Under the diagnosis of spitzoid melanoma, she was treated with excision biopsy and complete left axillary lymph nodes were dissected. She received interferon-alpha2b subcutaneously at a dose of 8 MIU per day, 3 times weekly for 12 months, and shows no recurrence.
