Reversible Dysphasia and Statins.
10.3346/jkms.2012.27.4.458
- Author:
Gordon Robert Wyndham DAVIES
1
Author Information
1. Department of Psychiatry, University of Wollongong, New South Wales, Australia. alienist@ihug.com.au
- Publication Type:Case Reports
- Keywords:
Dysphasia;
Statins;
Drug Interactions
- MeSH:
Anticholesteremic Agents/adverse effects/*therapeutic use;
Antihypertensive Agents/therapeutic use;
Anxiety/diagnosis;
Aphasia/diagnosis/*etiology;
Cytochrome P-450 Enzyme System/metabolism;
Depression/diagnosis;
Drug Interactions;
Female;
Fluorobenzenes/adverse effects/*therapeutic use;
Heptanoic Acids/adverse effects/*therapeutic use;
Humans;
Hypercholesterolemia/drug therapy;
Indapamide/therapeutic use;
Middle Aged;
Pyrimidines/adverse effects/*therapeutic use;
Pyrroles/adverse effects/*therapeutic use;
Sulfonamides/adverse effects/*therapeutic use
- From:Journal of Korean Medical Science
2012;27(4):458-459
- CountryRepublic of Korea
- Language:English
-
Abstract:
This paper presents a case of reversible dysphasia occurring in a patient prescribed atorvastatin in combination with indapamide. A milder dysphasia recurred with the prescription of rosuvastatin and was documented on clinical examination. This resolved following cessation of rosuvastatin. The case highlights both a need for a wider understanding of potential drug interactions through the CYP 450 system and for an increased awareness, questioning and reporting of drug side-effects.
