Photochemical Effect of the Photosensitizer Hemoporphyrin Derivative on MCF-7 Cell Line and Umbilical Cord Blood Hematopoietic Cells
- Author:
Lan-Ping DIAO
1
;
Jian-Min XU
;
Ming WU
;
Zhi-Jiang WU
Author Information
1. The Affiliated Forth Hospitol, Hebei Medical University, Shijiazhuang 050011, China.
- Publication Type:Journal Article
- From:
Journal of Experimental Hematology
2001;9(4):383-384
- CountryChina
- Language:Chinese
-
Abstract:
To study the effect of hemoporphyrin derivative(HPD) combined with laser irradiation on human breast tumor cell line MCF-7 and normal human umbilical cord blood-derived hematopoietic cells by using MTT assay. The results showed that HPD plus laser irradiation was more efficient for killing MCF-7 cells than normal human umbilical cord blood-derived hematopoietic cells. The photochemical effect with laser irradiation were higher than with light irradiation and it's effect on MCF-7 cells was higher gradually with the increase of HPD concentration.
