Diagnosis and treatment of lung aspergillosis after liver transplantation.
- Author:
Qi-yuan LIN
1
;
Yong-heng ZHAO
;
Lü-nan YAN
;
An-hua HUANG
;
Bo LI
;
Shi-chun LU
;
Yong ZENG
;
Tian-fu WEN
;
Ji-chun ZHAO
;
Nan-sheng CHENG
Author Information
- Publication Type:Case Reports
- MeSH: Adult; Aspergillosis; diagnosis; drug therapy; etiology; Female; Humans; Liver Transplantation; adverse effects; Lung Diseases, Fungal; diagnosis; drug therapy; etiology; Male; Middle Aged
- From: Chinese Journal of Surgery 2003;41(1):17-18
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVETo assess the diagnosis and treatment of invasive lung aspergillosis after liver transplantation.
METHODSRoutine sputum culture was performed. Itraconazole and fluconazole were used to prevent fungal infection prophylactically. Amphyotericin B was only used on aspergillosis. In 54 patients receiving, liver transplantation, 3 patients with lung aspergillosis were reviewed.
RESULTSOf the 3 patients 2 died and 1 recovered.
CONCLUSIONSOver-immunosuppression is a main risk factor for aspergillosis. Amphotericin B is still the best choice for the treatment of aspergillosis and its gradual, interrupted, low concentration administration, cooperated with itraconazole can ease the side effects.
