Extraskeletal Ewing's Sarcoma of the Hard Palate.
10.3346/jkms.2005.20.4.687
- Author:
Mi Seon KANG
1
;
Hye Kyoung YOON
;
Jung Bae CHOI
;
Jae Wook EUM
Author Information
1. Department of Pathology, Pusan Paik Hospital, College of Medicine, Inje University, Busan, Korea. pathkang@inje.ac.kr
- Publication Type:Case Report
- Keywords:
Sarcoma;
Ewing's;
Palate, Hard
- MeSH:
Adult;
Antigens, CD/analysis;
Cell Adhesion Molecules/analysis;
Humans;
Immunohistochemistry;
Male;
Oncogene Proteins, Fusion/genetics;
Palatal Neoplasms/genetics/metabolism/*pathology;
Palate, Hard/metabolism/*pathology;
Proto-Oncogene Protein c-fli-1/genetics;
Reverse Transcriptase Polymerase Chain Reaction;
Sarcoma, Ewing's/genetics/metabolism/*pathology;
Transcription, Genetic;
Vimentin/analysis
- From:Journal of Korean Medical Science
2005;20(4):687-690
- CountryRepublic of Korea
- Language:English
-
Abstract:
Extraskeletal Ewing's sarcoma (EES) is a rare soft tissue tumor morphologically indistinguishable from the more common Ewing's sarcoma of bone. We report a case of EES arising in the hard palate of 34-yr-old male patient. Microscopically, the monotonous small round cells without neuronal differentiation showed membranous positive immunoreactivity for MIC2/CD99 and vimentin. Ultrastructurally, the tumor cells showed a few intracytoplasmic organelles without evidence of neurosecretory granules or neurofilaments. The EWS-FLI1 chimeric gene was identified using the nested reverse transcriptase-polymerase chain reaction.
