Correlation between Plasma Level of Monocyte Chemotactic Protein 1 and Acute Aortic Dissection.
- Author:
Fan-Yan LUO
1
;
Zi-Hou LIU
1
;
Hai-He JIANG
1
;
Guo-Qiang LIN
1
Author Information
- Publication Type:Journal Article
- MeSH: Aneurysm, Dissecting; Aortic Aneurysm; Chemokine CCL2; Humans
- From: Acta Academiae Medicinae Sinicae 2015;37(3):352-354
- CountryChina
- Language:English
-
Abstract:
OBJECTIVETo investigate the potential association between monocyte chemotactic protein 1(MCP-1)in plasma and acute aortic dissection(AAD).
METHODSA total of 110 patients with Stanford type A AAD who had received emergent surgical treatment in Xiangya hospital from September 2011 to September 2014 were enrolled in as the study group;meanwhile,110 patients with simple hypertension who had received treatment in department of cardiology were chosen as the control group. The plasma level of MCP-1 was measured and then compared between these two groups.
RESULTSThe plasma level of MCP-1 in the study group was(257.79±86.52)pg/ml,which was significantly higher than that in control group [(136.57±48.84)pg/ml](P<0.001).
CONCLUSIONThere may be a correlation between plasma MCP-1 level and AAD.
