Diagnosis and treatment of primary gastric non-Hodgkin's lymphoma: analysis of 157 patients.
- Author:
Qinghao CUI
1
;
Xuebin DONG
;
Dianchang WANG
;
Xishan HAO
;
Jiacang WANG
;
Qiang LI
;
Dalu KONG
;
Ning LIU
Author Information
- Publication Type:Journal Article
- MeSH: Humans; Lymphoma, Non-Hodgkin; Neoplasm Staging; Prognosis; Retrospective Studies; Survival Rate
- From: Chinese Journal of Preventive Medicine 2002;36(7):502-504
- CountryChina
- Language:English
-
Abstract:
OBJECTIVETo seek the optimum treatment for patients with primary gastric non-Hodgkin's lymphoma and factors associated with prognosis.
METHODSA retrospective study was conducted on 157 primary gastric non-Hodgkin's lymphoma patients who had received operation for 45 years.
RESULTSThe X-ray diagnosis rate was 39.4% before operation. The diagnosis rate by gastroscopy was 52.7%. Among the 157 patients, 32 belonged to stage I(E), 40 stage II(E), 29 stage III(E), and 56 stage IV(E). All of the patients were received chemotherapy or radiation. The 3-, 5-, 10-, 15-year survival rates were 51.1% (69/135), 42.3% (55/130), 20.7% (23/111), and 13.5% (14/104).
CONCLUSIONSThe 3-, 5-year survival rates in stage I(E) and stage II(E) were 2 to 5 times higher than those in stage III(E) and IV(E) (P < 0.01). The 3-, 5-year survival rates of primary gastric non-Hodgkin's lymphoma were 60.2% (65/108) and 50.0% (52/104) respectively. The prognosis was better than the 5-year survival rate of gastric cancer patients with D(2) lymphodenectomy (33.3%). Early diagnosis and treatment are effective to prevent complications, enhance quality of patient's life, and prolong the survival.