Experience in diagnosis and treatment of ectopic ACTH syndrome.
- Author:
Daxin GONG
1
;
Yuji LI
;
Yili LIU
;
Shiguang XU
;
Kejian GUO
;
Zhixi SUN
;
Chuize KONG
Author Information
- Publication Type:Journal Article
- MeSH: ACTH Syndrome, Ectopic; Adrenocorticotropic Hormone; Cushing Syndrome; Humans
- From: Chinese Journal of Preventive Medicine 2002;36(7):525-527
- CountryChina
- Language:English
-
Abstract:
OBJECTIVESTo increase the diagnosis and treatment of ectopic ACTH syndrome.
METHODSThe data of 12 ectopic ACTH syndrome patients treated from 1985 to 1999 were retrospectively analyzed.
RESULTSTwelve patients were diagnosed as having ACTH syndrome by endocrinary test and primary tumors were ascertained by imaging examination. Follow-up from 7 months to 8 years showed 3 out of 5 patients with radical resection of primary tumor died. One patient with bilateral adrenorectomy was still alive. All patients received only chemotherapy except one died.
CONCLUSIONSPatients with Cushing's syndrome should be evaluated by endocrine test and followed up by imaging screen examination. The key points to increase treatment effect include early detection, localization and resection of primary tumors.
