Efficacy of compound Xuanju capsule in the treatment of chronic prostatitis with erectile dysfunction.
- Author:
Liang WANG
1
;
Ping LIANG
;
Wei YANG
;
Peng ZHOU
;
Xiao-Ke HUANG
;
Ji-Wen LIU
;
Wen-Feng CHAO
;
Hang YANG
;
Qing-Tang WANG
Author Information
- Publication Type:Journal Article
- MeSH: Adult; Capsules; Chronic Disease; Drugs, Chinese Herbal; therapeutic use; Erectile Dysfunction; complications; drug therapy; Humans; Levofloxacin; Male; Middle Aged; Ofloxacin; therapeutic use; Phytotherapy; Prazosin; analogs & derivatives; therapeutic use; Prostatitis; complications; drug therapy; Treatment Outcome; Young Adult
- From: National Journal of Andrology 2012;18(10):950-952
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVETo evaluate the efficacy and safety of Compound Xuanju Capsule (CXC) in the treatment of chronic prostatitis with erectile dysfunction (ED).
METHODSWe obtained NIH-CPSI and IIEF-5 scores from 132 chronic prostatitis patients with ED and divided the patients into a control (n = 70) and a treatment group (n = 62), the former treated with oral levofloxacin 0.2 g bid for 4-6 weeks and oral Terazosin at 2 mg qd for 2 months, and the latter with oral CXC once 2 capsules tid for 2 months in addition to the above.
RESULTSNone of the patients had serious medication-related adverse reactions. After treatment, the control group showed significantly decreased NIH-CPSI scores and slightly increased IIEF-5 scores as compared with the baseline (16.5 +/- 5.9 vs 25.1 +/- 5.5, P < 0.05 and 13.1 +/- 5.2 vs 11.3 +/- 4.5, P > 0.05), while the treatment group exhibited significant improvement in both NIH-CPSI (13.4 +/- 5.7 vs 25.5 +/- 5.3, P < 0.05) and IIEF-5 scores (17.5 +/- 6.5 vs 10.8 +/- 3.8, P < 0.05). The total effectiveness rate for ED was significantly higher in the treatment than in the control group (74.2% vs 20%, P < 0.05).
CONCLUSIONCompound Xuanju Capsule can significantly alleviate both the symptoms of chronic prostatitis and ED in the treatment of chronic prostatitis patients with ED.
