Primitive neuroectodermal tumor/Ewing's sarcoma of the penis in children: a case report and review of the literature.
- Author:
Da-Wei ZHANG
1
;
Mei JIN
;
Chun-Ju ZHOU
;
Hong-Cheng SONG
;
Xiao-Li MA
Author Information
- Publication Type:Case Reports
- MeSH: Child, Preschool; Humans; Male; Neuroectodermal Tumors, Primitive, Peripheral; Penile Neoplasms; Sarcoma, Ewing
- From: National Journal of Andrology 2012;18(12):1115-1118
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVETo investigate the clinical manifestations, pathological characteristics and treatment of primitive neuroectodermal tumor/Ewing's sarcoma (PNET/EWS) of the penis in children.
METHODSWe analyzed the clinical data of a case of PNET/EWS and reviewed relevant literature.
RESULTSThe patient was a 5-year-old boy, admitted for penis swelling with pain for 11 months. Biopsy showed a small round cell tumor, CD99 positive by immunohistochemical staining, with EWS translocation by fluorescence in situ hybridization on molecular biological examination. The tumor was confirmed to be PNET/EWS of the penis, and disappeared after 45 weeks of chemotherapy and local radiotherapy.
CONCLUSIONPNET/EWS of the penis is an extremely rare disease, with no specific clinical symptoms except penis enlargement with pain. Immunohistochemistry and molecular biological examination contribute to its diagnosis.
