Prognosis of patients with early enteral nutrition after gastrointestinal operation: a meta-analysis.
- Author:
Xiao-liang SHU
1
;
Kai KANG
;
Jing-xia ZHONG
;
Shu-rong JI
;
Ming-he WANG
;
Yong-sheng ZHANG
;
Da-han TANG
Author Information
- Publication Type:Journal Article
- MeSH: Digestive System Surgical Procedures; Enteral Nutrition; Gastrointestinal Diseases; surgery; Humans; Postoperative Complications; Prognosis; Randomized Controlled Trials as Topic
- From: Chinese Journal of Gastrointestinal Surgery 2013;16(11):1035-1040
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVETo systematically assess the effect of early enteral nutrition support after gastrointestinal operation on prognosis.
METHODSThe Cochrane Library, PubMed, CBM, CNKI, Wanfang, and VIP databases were retrieved via computer system for randomized controlled trails(RCTs) with early enteral nutrition support to patients undergoing gastrointestinal operation. Quality of studies was evaluated by the Cochrane Jadad rating scale. Nutrition indexes, bowel function indices, postoperative complications, health-economics indices were collected. Meta-analysis was conducted with RevMan 5.2.
RESULTSEleven relevant RCTs studies with 1087 cases were enrolled, including 541 patients in the study group(early enteral nutrition) and 546 in the control group. Meta-analysis showed that patients in the study group had significantly higher levels of plasma albumin and prealbumin than those in the control group(WMD=2.87, 95%CI:1.03-4.71; WMD=0.04, 95%CI:0.02-0.05). The time of postoperative bowel ventilation in the study group was significantly shorter than that in the control group(WMD=4.10, 95%CI:-5.38--2.82). The postoperative complication rate in the study group was significantly lower as compared to the control group(RR=0.64, 95%CI:0.44-0.93).
CONCLUSIONEarly enteral nutrition support after gastrointestinal operation is safe and effective, which can improve the nutritional status, promote bowel function return, and reduce postoperative complication rate.
