Risk factors and prognosis of liver metastasis from gastric cancer.
- Author:
Xiang HU
1
Author Information
1. Department of General Surgery, The First Affiliated Hospital, Dalian Medical University, Dalian 116011, China. g.Shuxian@aliyun.com.
- Publication Type:Journal Article
- MeSH:
Adenocarcinoma;
Humans;
Liver Neoplasms;
diagnosis;
secondary;
Lymphatic Metastasis;
Prognosis;
Risk Factors;
Stomach Neoplasms;
pathology;
Survival Rate
- From:
Chinese Journal of Gastrointestinal Surgery
2014;17(2):108-111
- CountryChina
- Language:Chinese
-
Abstract:
Liver metastasis from gastric cancer is a major cause of cancer-related death. Since liver metastasis from gastric cancer is usually associated with other non-curative factors, such as peritoneal metastasis, lymph node metastasis and extensive intrahepatic metastasis, the hepatic resection rate was low and the prognosis was poor. The main risk factors of liver metastasis were serosal invasion, p(+), N3-N4, differentiated histologic type, medullary type of poorly differentiated adenocarcinoma, vascular invasion, and overexpression and mutation of VEGF, P53 and c-erbb-2. The 5-year survival rate after hepatic resection of synchronous and metachronous liver metastasis from gastric cancer ranged from 11% to 42%. Appropriate patient selection for hepatic resection may confer a better prognosis of liver metastasis from gastric cancer.
