Two new phenylpropanoid glycosides from the aerial parts of.
- Author:
Chuangfeng ZHANG
1
;
Jian ZHOU
2
;
Jingzhi YANG
1
;
Chuangjun LI
1
;
Jie MA
1
;
Dan ZHANG
1
;
Dongming ZHANG
1
Author Information
1. State Key Laboratory of Bioactive Substance and Function of Natural Medicines, Institute of Materia Medica, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100050, China.
2. State Key Laboratory of Bioactive Substance and Function of Natural Medicines, Institute of Materia Medica, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100050, China
- Publication Type:Journal Article
- Keywords:
Cuneataside E;
Cuneataside F;
Extraction and isolation;
Hepatoprotective activity;
Lespedeza cuneata;
Phenylpropanoid glycosides
- From:
Acta Pharmaceutica Sinica B
2016;6(6):564-567
- CountryChina
- Language:English
-
Abstract:
Two new phenylpropanoid glycosides named cuneataside E () and cuneataside F (), were isolated from the aerial parts of(Dum. Cours.) G. Don, whose structures wereandisomer, respectively. Their structures were elucidated on the basis of comprehensive spectroscopic analysis (UV, IR, HR-ESI-MS, 1D and 2D NMR). Inbioassays at 10 μmol/L, compoundshowed moderate hepatoprotective activity against-acetyl--aminophenol (APAP)-induced toxicity in HeG2 cells.
