Diversity of intestinal microflora in patients with depression after stroke.
- Author:
Wen-Tao FAN
1
;
Yong-Mei YAN
;
Yu-Long BIE
;
Qian WANG
Author Information
- Publication Type:Journal Article
- MeSH: Adult; Case-Control Studies; Depression; complications; microbiology; Gastrointestinal Microbiome; High-Throughput Nucleotide Sequencing; Humans; Intestines; microbiology; Stroke; complications; psychology
- From: Journal of Southern Medical University 2016;36(10):1305-1311
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVETo investigate the changes in the population and distribution intestinal microflora and their relationship with depression in post-stroke patients.
METHODSFecal specimens were obtained from 32 patients with post-stroke depression and 30 healthy adults for gene sequencing of 16S RNA V3 region of the intestinal microorganism using Roche/45 high-throughput sequencing platform.
RESULTSThe genus and species of intestinal bacteria showed significant differences between the post-stroke patients and health adults.
CONCLUSIONSignificant changes in the structure of intestinal flora occur in patients with post-stroke depression.
