Analyses of EGF and TNF contents in fetal wound healing process.
- Author:
Guoping FENG
1
;
Guangci SUN
;
Zhengyu GUAN
Author Information
- Publication Type:Journal Article
- MeSH: Animals; Epidermal Growth Factor; metabolism; Female; Fetus; metabolism; surgery; Pregnancy; Rabbits; Radioimmunoassay; methods; Time Factors; Tumor Necrosis Factor-alpha; metabolism; Wound Healing
- From: Chinese Journal of Plastic Surgery 2002;18(6):341-342
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVETo investigate the role of EGF and TNF in the fetal wound healing process.
METHODSOn a fetal wound healing model with the maternal rabbit on 22-23 days of pregnancy (term = 31-32 days), the contents of EGF and TNF were analyzed with a RIA kit, compared to the maternal rabbit group and the adult rabbit group.
RESULTSThe EGF and TNF contents in the fetal wound were both increasing 3 days after the operation and maintained in a high level until the 7th day of the wound healing process(P < 0.05). However, the EGF and TNF contents in the maternal and adult rabbit groups were only kept at a high level during the 3 days after the surgery.
CONCLUSIONThe results are indicated that the EGF and TNF may play an important role in fetal wound healing.
