Change of expression of P-selectin in avulsion-injured vessels.
- Author:
Bao-hua PAN
1
;
Hui-yuan LI
;
Kai-hua LU
;
Shu-zhong GUO
;
Wei XIA
;
Bing-lun LU
;
Sheng-xi WU
Author Information
- Publication Type:Journal Article
- MeSH: Animals; Endothelium, Vascular; P-Selectin; metabolism; RNA, Messenger; metabolism; Vascular System Injuries; genetics; metabolism
- From: Chinese Journal of Plastic Surgery 2003;19(4):288-290
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVETo determine the change of P-selectin in avulsion-injured vessels.
METHODSDifferent stretch forces of 60, 70, 80 and 90 g were applied to a vascular injury model. The expression changes of P-selectin were evaluated by RT-PCR.
RESULTSThe expression of P-selection mRNA in the injured vessels increased with the stretch force.
CONCLUSIONThe result associated with our previous study indicated that P-selectin may be involved in thrombosis.