A clinical study of flap necrosis protection with dexamethasone.
- Author:
Jing-min CAO
1
;
Biao WANG
;
Kai-hua LU
;
Yan HAN
;
Shu-zhong GUO
;
Yu-hong LANG
;
Ling CHEN
Author Information
- Publication Type:Journal Article
- MeSH: Adolescent; Adult; Dexamethasone; pharmacology; therapeutic use; Female; Humans; Male; Middle Aged; Necrosis; Surgical Flaps; pathology
- From: Chinese Journal of Plastic Surgery 2003;19(6):433-435
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVEThis clinical study was to find an effective method to prevent flap from necrosis.
METHODSWhen a flap showed blood flow problems, dexamethasone of 0.3 mg/kg was given intravenously for 2 days. Then the dose was decreased to 0.2 mg/kg at the third and the fourth day. At the fifth and the sixth day, dexamethasone of 0.1 mg/kg was given.
RESULTSA total of 51 flaps with blood flow problems was treated with this method. Thirty of them recovered completely; 18 survived mostly and 3 failed.
CONCLUSIONEarly application of dexamethasone can effectively ameliorate blood flow problems of the flap.
