Study on experimental factors for extraction of alkaloids from Aconitum carmichaili.
- Author:
Chun-mei LIANG
1
;
Ru-qing YAN
Author Information
- Publication Type:Journal Article
- MeSH: Aconitum; chemistry; Alkaloids; analysis; isolation & purification; Ethanol; Particle Size; Plants, Medicinal; chemistry; Powders; Technology, Pharmaceutical; methods; Time Factors
- From: China Journal of Chinese Materia Medica 2004;29(3):222-224
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVETo determine the suitable conditions for extracting alkaloidals from Aconitum carmichaili.
METHODUsing methods in Chinese Pharmacopeia for determining yields of extraction, which include spectrometry and single-factor tests, we investigated vavious factors that would affect the extraction of alkaloids from Aconiti.
RESULTThe suitable extractant was 85% ethanol, starting material was medium-size powder of aconiti, 10 times of the volume of the solvent was used in extraction for twice 1.75 h each time. The extraction yield was 1.21%, with a content of 0.33% alkaloids.
CONCLUSIONExtraction conditions determined with single factor test was consistent and feasible.
