Research progress of neuroprotective mechanisms of Gastrodia elata and its preparation.
- Author:
Xiao-fang SUN
1
;
Wei WANG
;
Dan-qiao WANG
;
Gui-you DU
Author Information
1. Geriatrics Institute, Xiyuan Hospital, China Academy of Traditional Chinese Medicine, Beijing 100091, China. sxfnet@sina.com
- Publication Type:Journal Article
- MeSH:
Animals;
Antioxidants;
pharmacology;
Apoptosis;
drug effects;
Calcium;
metabolism;
Drugs, Chinese Herbal;
isolation & purification;
pharmacology;
Excitatory Amino Acids;
antagonists & inhibitors;
Gastrodia;
chemistry;
Humans;
Neuroprotective Agents;
pharmacology;
Nitric Oxide;
metabolism;
Nitric Oxide Synthase;
metabolism;
Plants, Medicinal;
chemistry
- From:
China Journal of Chinese Materia Medica
2004;29(4):292-295
- CountryChina
- Language:Chinese
-
Abstract:
The effects of Gastrodia elata on preventing decrepitude and advancing memory are closely associated with its neuroprotective activity. Previous researches proved that G. elata, its active components and preparations played a neuroprotective role by affecting the excitotoxicity, nitric monoxide (NO) system, neuroglia, biomembrane, oxidative neurotoxicity, apoptosis et al. Recent researches also suggest that reducing energy metabolism impairment, anti-inflammatory and immune modulating function may be new research targets of neuroprotective mechanism of G. elata.
