Studies on the chemical constituents from culbs of hybridized Bulbus Fritillariae Ussuriensis.
- Author:
Han-li RUAN
1
;
Yong-hui ZHANG
;
Xu-chu PAN
;
Tao DONG
;
Ji-zhou WU
Author Information
- Publication Type:Journal Article
- MeSH: Cevanes; chemistry; isolation & purification; Fritillaria; chemistry; classification; genetics; Glucosides; chemistry; isolation & purification; Hybridization, Genetic; Molecular Structure; Plant Roots; chemistry; Plants, Medicinal; chemistry; classification; genetics
- From: China Journal of Chinese Materia Medica 2004;29(4):331-334
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVETo study the chemical constituents of hybridized Bulbus Fritillariae Ussuriensis.
METHODThe chemical constituents were isolated by silica column chromatography and their structures were identified by physical and chemical eveidences and spectral analysis (IR, 1H-NMR, 13C-NMR, 2D-NMR, MS).
RESULTSeven compounds were obtained and identified as (20S,25S)5alpha, 14alpha, 17beta-cevanine-6beta-hydroxy-3-one (hupehenirine, ZF1), (20S,25S)5alpha, 14alpha, 17beta-cevanine-3beta-hydroxy-6-one (hupehenizine, ZF2), (20R,25S)5alpha, 14alpha-cevanine-3beta,20beta-dihydroxy-6-one (peiminine, verticinone, ZF3), (20S,25S)5alpha, 14alpha, 17beta-cevanine-3beta, 6beta-dihydroxy (hupehenine, ZF4), (20R,25S)5alpha, 14alpha-cevanine-3beta, 6beta, 20beta-trihydroxy (isoverticine, ZF5), (20R,25S)5alpha, 14alpha-cevanine-3beta, 6alpha, 20beta-trihydroxy (peimine, verticine, ZF6), (20S,25S)5alpha, 14alpha, 17beta-evanine-6beta-hydroxy-3beta-O-beta-D-glucoside (hupeheninoside, ZF7).
CONCLUSIONCompounds ZF1-7 were isolated from hybridized Bulbus Fritillariae Ussuriensis for the first time.
