Clinicopathologic characteristics of primary thyroid-like follicular carcinoma in kidney.
- Author:
Huan-wen WU
1
;
Wen-jing CHEN
;
Yan YOU
;
Quan-cai CUI
;
Tong-hua LIU
Author Information
- Publication Type:Case Reports
- MeSH: Adenocarcinoma, Follicular; metabolism; pathology; Adult; DNA-Binding Proteins; metabolism; Diagnosis, Differential; Female; Follow-Up Studies; Humans; Keratin-7; metabolism; Kidney Neoplasms; metabolism; pathology; Nephrectomy; methods; Neprilysin; metabolism; Thyroid Neoplasms; metabolism; pathology; Transcription Factors; Vimentin; metabolism
- From: Chinese Journal of Pathology 2013;42(1):37-41
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVETo explore the clinicopathological characteristics of primary thyroid-like follicular carcinoma of the kidney.
METHODSA case of primary thyroid-like follicular carcinoma of the kidney was studied with histology and immunohistochemical staining, and its clinical and pathological findings were further analyzed with review of the literature.
RESULTSThe patient was a 26-year-old asymptomatic woman who had a kidney mass during her annual physical examination. The tumor was well-circumscribed. Pathologically, the tumor showed follicular structures with colloid-like material in the lumina. Immunohistochemically, the tumor cells showed intense staining for CK7 and vimentin and negative for thyoid transcripation factor-1, thyroglobulin, thyoid peroxidase and RCC.
CONCLUSIONSThe diagnosis of primary thyroid-like follicular carcinoma of the kidney is based on the characteristic follicular architecture with colloid-like material, and the metastasis from a thyroid follicular carcinoma must be excluded clinically and pathologically before making the final diagnosis.
