Differences in gene expression between Taxus chinensis cells during Taxol-synthesis phase and those during non-Taxol-synthesis phase.
- Author:
Guo-Bin HU
1
;
Xing-Guo MEI
;
Wei GONG
;
Tie KE
Author Information
1. School of Life Science and Technology, Huazhong University of Science and Technology, Wuhan 430074, China. hugbonline@263.net
- Publication Type:Journal Article
- MeSH:
Gene Expression Regulation, Developmental;
Gene Expression Regulation, Plant;
Paclitaxel;
biosynthesis;
RNA, Messenger;
genetics;
metabolism;
Taxus;
genetics;
growth & development;
metabolism;
Time Factors
- From:
Chinese Journal of Biotechnology
2002;18(4):512-515
- CountryChina
- Language:Chinese
-
Abstract:
In plant, evocation of secondary metabolism is associated with complex biochemical and molecular events that are regulated by developmental and environmental factors. In order to get more information about Taxol biosynthesis, comparison of mRNA populations from Taxus chinensis cells during Taxol-synthesis phase and those during non-Taxol-synthesis phase were performed by mRNA differential display. The results suggested that genes specifically expressed in the Taxol-synthesis phase might be involved in Taxol biosynthesis.
