Food-grade gene expression systems for lactic acid bacteria.
- Author:
Zhen-Zhong ZHANG
1
;
Xiu-Zhu CHEN
;
Shi-Fang JIA
;
Mei-Ling CHEN
;
Lian-Dong HUAN
Author Information
1. Research Center for Molecular Microbiology, State Key Laboratory of Microbial Resources, Institute of Microbiology, Chinese Academy of Sciences, Beijing 100080, China.
- Publication Type:Journal Article
- MeSH:
Food Industry;
methods;
standards;
Food Microbiology;
Gene Expression Regulation, Bacterial;
Lactococcus lactis;
genetics;
growth & development
- From:
Chinese Journal of Biotechnology
2002;18(4):516-520
- CountryChina
- Language:Chinese
-
Abstract:
Lactic acid bacteria (LAB) are important industrial microorganism used in the production and preservation of food-stuffs. Recently, considerable advances have been made in the genetics and molecular biology of LAB. These have resulted in the construction of food-grade gene expression systems for these bacteria. This paper aims to review the essential features for food-grade systems, food-grade selection markers, food-grade controlled gene expression and food-grade inducible signaling molecule, and recent developments on food-grade cloning and expression systems for LAB. These gene expression systems have great potential for studies on gene expression and regulation in LAB and a variety of bioprocessing application in industrial fermentations.
