Correlative analysis advance of chemical constituents of Polyporus umbellatus and Armillaria mellea.
10.19540/j.cnki.cjcmm.20170512.009
- Author:
Jing-Wen HUANG
1
;
Chang-Jiang-Sheng LAI
2
;
Yuan YUAN
2
;
Min ZHANG
3
;
Jun-Hui ZHOU
2
;
Lu-Qi HUANG
2
Author Information
1. School of Traditional Chinese Medicine, Guangdong Pharmaceutical University, Guangzhou 510006, China.
2. State Key Laboratory of Dao-di Herbs, National Resource Center for Chinese Materia Medica, China Academy of Chinese Medical Sciences, Beijing 100700, China.
3. Hubei Mengyang Pharmaceutical Co., Ltd, Jingmen 448124, China.
- Publication Type:Journal Article
- Keywords:
Armillaria mellea;
chemical constituents;
mycelium of Polyporus umbellatus;
sclerotia of Polyporus umbellatus;
secondary metabolites;
symbiotic relationship
- From:
China Journal of Chinese Materia Medica
2017;42(15):2905-2914
- CountryChina
- Language:Chinese
-
Abstract:
Medicinal Polyporus umbellatus is the dry sclerotia of P. umbellatus, with the effect of diuresis; Armillaria mellea is a parasitic fungus which can infect plants up to 300 genera, with sedative, anticonvulsant and some other biological activities. As the medicinal value of P. umbellatus and A. mellea is increasingly wide concerned, the market quantity demanded of them is gradually increased and the demand outstrips the supply. The symbiotic A. mellea and P. umbellatus are both the medicinal and edible fungi with diverse activities, including hypoglycemic action, improve immunity and antitumor and so on. The growth of the sclerotia forming from the mycelium of P. umbellatus is related to the infection of the symbiotic A. mellea and their secondary products. In this study, by comparing the chemical constituents of the mycelium and sclerotia of P. umbellatus and A. mellea, we found that they all produced steroids and nitrogen-containing heterocycles. The sclerotia of P. umbellatus and A. mellea also produced triterpenes secondary metabolites. In addition, the mycelium and infected sclerotia of P. umbellatus mainly produced different steroids, and the sclerotia produced some other special secondary metabolites, such as long-chain fatty acids, ceramides, phenol and so on. By analyzing above all kinds of differences, speculated that these may be caused by the infection of the symbiotic A. mellea which mainly produced sesquiterpenes, diterpenes and other secondary metabolites. The contents and types of compounds of P. umbellatus and A. mellea are closely related to their symbiosis and reproduction, therefore, many symbiosis mechanisms should be found by utilizing more molecular biology technology to elucidate this complex symbiotic infection and provide scientific basis for improving the yield and quality of P. umbellatus and A. mellea.
