Interdigitating dendritic cell sarcoma-a case report with literature review.
- Author:
Wen-Jin GAO
1
;
Ri ZHANG
;
Hong-Xia QIU
;
Yi-Min SHEN
;
Xu-Hui ZHANG
;
Sheng-Li XUE
;
Yue HAN
Author Information
- Publication Type:Case Reports
- MeSH: Adult; Antigens, CD; analysis; Antigens, Differentiation, Myelomonocytic; analysis; Antineoplastic Combined Chemotherapy Protocols; therapeutic use; Bleomycin; administration & dosage; Dacarbazine; administration & dosage; Dendritic Cell Sarcoma, Interdigitating; diagnosis; drug therapy; metabolism; Doxorubicin; administration & dosage; Humans; Immunohistochemistry; Male; S100 Proteins; analysis; Treatment Outcome; Vinblastine; administration & dosage
- From: Chinese Journal of Hematology 2005;26(4):232-234
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVETo report a case of interdigitating dendritic cell sarcoma (IDCS).
PATIENT MATERIALThe patient was a 41-year-old man with a lymph node bulging in the left neck. Laboratory examination of peripheral blood and bone marrow was abnormal. The diagnosis of IDCS was made by immunohistochemistry and electron microscopy. Treatment of this patient with ABVD regimen (adriamycin, bleomycin, vinblastine, dacarbazine) resulted in obvious improvement, but did not control the tumor infiltration.
CONCLUSIONIDCS has no distinctive clinical or pathohistological characteristics. Immunohistochemistry and electron microscopy are crucial in distinguishing it from other histiocytic/dendritic cell neoplasms. IDCS displays an aggressive behaviour, and the responses to chemotherapy are variable.
